Shinichirou Nakagami was living the life other boys from his grade could only dream of—staying under the same roof as prodigal student Hiromi Yuasa. However, the bright and cheerful Hiromi has been depressed and cold at home ever since her mother passed away. While he is the subject of the ignorant jealousy of his peers, rumors begin to spread when Shinichirou meets Noe Isurugi—a girl known for cursing classmates, curses which always end up becoming reality. Noe curses Shinichirou as well, but two pits are created when you curse someone, and her curse on Shinichirou comes back to bite her in the form of a raccoon to her beloved chicken, Raigomaru. Despite this, she does not shed a single tear; Noe had had her tears stolen. For Noe to be able to cry again, she would need the tears of another, and Shinichirou knows a person whose tears he wants to take away.

It was officially announced at the Dengeki Game Festival 2015 event that Strike the Blood will be getting a two-episode OVA series to be released at the end of 2015. The OVA will be an original story written by Gakuto Mikumo.

In order to uncover the "end of the sky," as spoken of in ancient mythology, Kal-el Albus is sent to Isla, an island in the sky. There he attends Cadoques High's Aerial Division, where he enjoys a carefree life with his schoolmates. That is...until a surprise attack by the air tribe drags Isla into a bloody war. (Source: NIS America)

OVAs bundled with the 15-17th volumes of the Mushibugyou manga.