Following a catastrophic war against a race of giants known as the Zentradi, humanity has escaped towards the center of the galaxy aboard a fleet of colonial vessels called the Macross Frontier. As the extraterrestrial threat is left further and further behind, life on Macross Frontier proceeds as usual. In the year 2059, a young mecha pilot trainee named Alto Saotome and his colleagues are preparing to perform an accompanying routine for the famous singer Sheryl Nome, who has come to Macross Frontier for a concert. During the performance, a biomechanical alien species known as the Vajra make a sudden appearance, breaking through the defensive perimeter surrounding the vessel and crash-landing near the concert venue, plunging the entire city into chaos. As the concertgoers evacuate, a young girl named Ranka Lee is left behind and gets targeted by the Vajra, but she is saved at the last minute by Alto. Following these events, the Strategic Military Services program notes Alto's skill in battle, resulting in his recruitment to combat the new alien threat. [Written by MAL Rewrite]

After surviving a vampire attack, Koyomi Araragi notices that his friend and savior, Tsubasa Hanekawa, has been acting strange. When he happens to cross paths with her on his way to a bookstore and sees she has a bandage on her face, he knows something must definitely be wrong. Araragi wants to help her, but Hanekawa assures him that her wound is just something she received at home and that he should not concern himself with it. But when a white cat with no tail is hit and killed by a car, the pair bury the creature and the real trouble begins. When Araragi later pays a visit to his friend Meme Oshino and recounts the day's events, he is informed what they have buried is actually an apparition, one perfect for Hanekawa in her current state. Tasked with finding his friend to confirm her safety, he discovers that she has attacked her parents, possessed by the "Sawari Neko." Now, it is up to Araragi to help Hanekawa as she once helped him. [Written by MAL Rewrite]

While the young Angelique lives out her days peacefully in her school, attacks from the monstrous Thanatos has been increasing everywhere else. Two Purifiers show up one day, men with the power to exterminate the Thanatos. One of them, Nyx, attempts to convince Angelique to join them in their work, as she has the power to be the only female Purifier. As Angelique hesitates, a Thanatos shows up in their school. Nyx and the other Purifier, Rayne, fight a losing battle. With her classmates falling prey to the Thanatos, and the Purifiers beaten to submission, Angelique's desire to save everyone awakens. She became the only female Purifier in their land of Arcadia, the one known as the "Queen's Egg".

High school students Yuma Okazaki and Hotaru Mizushina are childhood friends. With their respective boyfriends, Takeda and Fujiwara, their lives couldn't be more perfect. From playing in school to going on group dates, it seems nothing can break their bond. However, during one such group date, Hotaru makes an unexpected move. While Takeda and Fujiwara are distracted, she begins stroking Yuma's thighs. Taken aback by this peculiar action, Yuma awkwardly retreats to the toilets, followed shortly by her aggressor. Now in private, Hotaru forces the innocent Yuma into a locked cubicle and whispers into her ear: "You'll be more nervous with a boy; I'll help you practice." [Written by MAL Rewrite]