Saya Otonashi is a seemingly ordinary girl living a mundane life with her adoptive family in Okinawa City. In fact, her only peculiarities are suffering from anemia and being unable to remember any of her life beyond the previous year. However, Saya's forgotten past quickly comes back to haunt her—one night, she is attacked at school by a creature that feeds on human blood. Just when all hope seems lost, a mysterious man named Haji appears and fends off the creature temporarily. But when her rescuer forces her to drink his blood, Saya suddenly enters a trance and slays the monster with ease, using her own blood as a catalyst. Saya then learns of an organization named Red Shield, founded for the sole purpose of defeating the hellish beasts. Now Saya and Haji must work together with Red Shield to fight these fearsome monsters and unlock the secrets to the girl's past.

An alternate retelling of the beginning of the original series. Mikako and Tsutomu lived next door to each other since they were little. They both attend an art school, where Mikako is pursuing her dream of being a fashion designer. They formed a club called Akindo with several of their friends. Akindo participates in flea markets, where they sell their creations—clothes, dolls, and artwork.

The protagonist, Kouda Mikako, is a student of "Yaza Gaku". Specialising in fashion design, Mikako dreams of becoming a fashion designer with her own brand. Living next to her is her childhood friend, Yamaguchi Tsutomu. Even though they have been close since they were young, they share a platonic friendship. However, Tsutomu has been gaining popularity, especially with the girls, because he seems to resemble a popular vocalist from a band and somehow, Mikako begins to see him in a different light. This is a story about how youths cope with dreams, love and friendship.

With reports of monsters terrorizing the reactor at Mount Nibel, the Shinra Electric Power Company dispatches their elite fighting force SOLDIER to investigate. Accompanied by fellow SOLDIER First Class Zack Fair and a small contingent of company guards, the war hero Sephiroth is to assess the condition of the Mako reactor at the behest of the company. In Nibelheim, the village that the reactor powers, Sephiroth discovers the source of the monsters and the origins of Shinra's legendary Jenova Project. Running through the woods months later, Zack is no longer the hero he once dreamt of becoming. He flees from the General Affairs Department of the Shinra Electric Power Company, better known as the Turks, who desperately seek to bury the evidence living within the two.