While the young Angelique lives out her days peacefully in her school, attacks from the monstrous Thanatos has been increasing everywhere else. Two Purifiers show up one day, men with the power to exterminate the Thanatos. One of them, Nyx, attempts to convince Angelique to join them in their work, as she has the power to be the only female Purifier. As Angelique hesitates, a Thanatos shows up in their school. Nyx and the other Purifier, Rayne, fight a losing battle. With her classmates falling prey to the Thanatos, and the Purifiers beaten to submission, Angelique's desire to save everyone awakens. She became the only female Purifier in their land of Arcadia, the one known as the "Queen's Egg".

Since childhood, Aoba Suzukaze has loved the Fairies Story game series, particularly the character designs. So when she graduates from high school, it is no surprise that she applies to work at Eagle Jump, the company responsible for making her favorite video game. On her first day, she is excited to learn that she will be working on a new installment to the series: Fairies Story 3—and even more so under Kou Yagami, the lead character designer. In their department are people who share the same passion for games. There is Yun Iijima, whose specialty is designing monsters; the shy Hifumi Takimoto, who prefers to communicate through instant messaging; Hajime Shinoda, an animation team member with an impressive figurine collection; Rin Tooyama, the orderly art director; Shizuku Hazuki, the game director who brings her cat to work; and Umiko Ahagon, the short-tempered head programmer. New Game! follows Aoba and the others on their adventure through the ups and downs of game making, from making the perfect character design to fixing all the errors that will inevitably accumulate in the process. [Written by MAL Rewrite]

​It has been a year since Aoba Suzukaze started working at the Eagle Jump game company. In that time, she and her eccentric coworkers in the character design department have worked hard to release the company's newest game: Fairies Story 3. With their latest title now complete, a new project must begin—starting with a contest to decide the character designs for the upcoming game. Through hard work, dedication, and some guidance from the previous character designer, Kou Yagami, Aoba wins the contest and begins her new role as lead character designer. However, her new job is not an easy one. In addition to having extra work and longer hours, Aoba questions whether she is the right fit for the job. New Game!! continues as Aoba overcomes her inexperience with the help of her friends and coworkers, willing to face any challenge to make Eagle Jump's newest creation, a cutesy game called Peco. [Written by MAL Rewrite]

Lamune is an ordinary 4th grade boy who loves playing video games. He buys one from a peddler girl and helps her sell the rest. At home, he plays the game called "King Sccasher" & beats it. The peddler girl then comes out of the TV screen and asks for his help, calling him "The Blood Relative of the Chosen Hero Lamuness". She is Princess Milk and takes him to Hara-Hara World where his role is to revive the Guardian Knights. To do this, he had to find an unlock the shrine which held Tama-Q, a robot who became Lamuness' Advisor Robot, and key to freeing the Guardian Knights. All of the Knights are free-thinking mechas except for King Sccasher which is piloted by Lamuness. Opposing Lamuness is Don Harumage and his minions Da Cider and Lesuka. (Source: ANN)