The story of Sanzo and his three companions in their quest to the west, to stop the resurrection of Gyuumao. On the way they are fighting youkai, getting into trouble and helping the townspeople.

A devil-girl with the face of an angel and a heart of gold, blond Betty falls in love with an earthbound gangster, Danpei Kimogawa, when they meet in a rainstorm. They end up living together in a Tokyo highrise apartment, though Danpei has trouble coping with his new witch and demon in-laws dropping in at inopportune moments. Betty has actually been sent to the human world on a mission to defeat the demon Lutan. While Betty continues her task, her skeletal grandmother sends nubile nymphs to tempt Danpei and see if he is suitable husband material.

"First muscle training animation ever," a 16-year-old girl named Hinako leads exercises in push-ups, sit-ups, and squats. Hinako was once a human, but she was turned into an anime character when she was a second-year middle-school student.

The episode is set during a school festival where Shinobu is assigned to write a script and make outfits for her class play. Youko and Alice notice that Shinobu is sleepy every morning and are worried that she might be getting tired of all the work. Will Shinobu be able to successfully complete all her tasks in time?